It helps in increasing potential lifespans for dogs with congestive heart failure. I assume you are quite certain that youre not also giving a diuretic, either separately or combined, as these are very commonly used in heart disease. If the illnesses began after starting pimobendan, they could well be genuine side-effects of the drug. . If you want to take a closer look, Ive included the reported side effects from both studies in two tables after the references. There are dogs for whom Vetmedin would be helpful. That then leads to questions like. My mini poodle is on vetmedin, hydrocodone homatropine and furosemide. There are, however, cases in which dogs may die soon or later after starting to take Vetmedin. Hi There, My 11 year Old Springier Spaniel, was diagnosed with a hear murmur, and on Xray, diagnosed with an enlarged heart and put on Pimobendan & Frusemide. Part 28: 5-alkylidene-6-phenyl-3(2H)-pyridazinones, a new family of platelet aggregation inhibitors. Let's discuss why fish oil could have killed your dog, its benefits and risks, and how to include it in your dog's diet safely. If the end goal is improved lifespan and quality of life, it should be straightforward to go out on a limb and use this drug given what we know. You auscultate a grade 4/6 systolic, left apical heart murmur. Pimobendan (brand name: Vetmedin) is a heart medication used to treat dogs with congestive heart failure (CHF), usually caused by either dilated cardiomyopathy or valvular insufficiency. There are four things you can do to minimize the chances of Vetmedin killing your dog. He had been doing great but every so often has a hard time breathing. If your dog has an adrenal tumor growing on the adrenal glands, your vet may suggest abdominal surgery to remove it. CHF can develop for reasons other than DMVD or DCM. Yoshiyuki R, Nakata TM, Fukayama T, et al. Preclinical DCM (Stage B2) I have an 11 yo Doberman who was diagnosed with DCM in March of 2022 he was put on Furosemide 1 tab twice a day (up to 4x a day), Enalapril 3 tabs twice a day and Pimobendan 1 tab twice a day. She started having ataxia, loss of appetite, and became very winded from just walking outside. While both MVD and DCM may happen to any dog breed, particular breeds are more susceptible to these diseases than others. [From Tufts Febuary 2010 Issue] CONGESTIVE HEART FAILURE IN DOGS: OVERVIEW 1. Her breathing sounds better . Thats a difficult one to unpack, and Im not sure I can comment. So you cant altogether rule out the possibility of Vetmedin killing a dog directly. Though you dont have to hire a lawyer for this, the compensation or money return you get is relatively smaller than in other courts. A study on Pimobendan (PB) found in Vetmedin, conducted by the World Small Animal Veterinary World Congress Proceedings, went on to test whether PB slows down the onset of heart failure and improves life quality in dogs. Vetmedin is deemed a prescription medication and requires your vets approval before being authorized to purchase and give it to your dog. Therefore, its possible that your dog does not need it, and that radiography or ultrasonography would help answer the question. As a fellow dog owner who lost a dog due to a blood disorder, I, too, know how painful and raw it feels to lose a beloved pet. On the basis of its positive inotropic effects combined with arteriovenous dilation, it is classified as an inodilator.1. Intake should occur exactly an hour before breakfast and another hour before dinner in the evening (about 12 hours apart). Pimobendan (Vetmedin) is a commonly prescribed heart medication used by veterinarians. That then leads to questions like, did Vetmedin killed my dog? It helps in increasing potential lifespans for dogs with congestive heart failure. Vetmedin can come in two forms: a chewable tablet or capsule. . Much depends on what stage, in the course of congestive heart failure progression, Vetmedin usage was initiated. Negotiate for a settlement or bring a lawsuit with a lawyers assistance. There are instances in which dogs may seem to die soon after starting to take Vetmedin. The answer your question comes down to whether you are prepared to go with the evidence or not. Another study showed pimobendan's usefulness in improving the quality of life by reducing heart . Should I reintroduce the Frusemide in these next two weeks? There should be no practical difference between pimobendan and Vetmedin in any developed country with good quality control regulations as they are the same active ingredient. Try to avoid reading too much into user reviews about these drugs here we are dealing with dogs with severe disease, and people often mistake the illness for side-effects of the drug. Pimobendan is available as Vetmedin (vetmedin.com) in oblong, half-scored chewable tablets (1.25 mg, 2.5 mg, 5 mg, or 10 mg). I seem to recall he didnt respond as well as anticipated to the full dose of Cardisure so our vet halved the dose. My 13-14 year old rescued Pomeranian will only take Pimobentan with food. This may be the case if the dogs body reacts badly to the Vetmedin. He didnt appear to have any fluid in lungs, but they thought they saw something possibly starting in his lungs. Can Vetmedin ActuallyKill My Dog? For benazepril it was 140. But he still was very active and no symptoms. She has side effects, no energy, confusion, incontinence and vomiting. This drug is used for treating a number of heart conditions in dogs, such as congestive heart failure (CHF), mitral valve disease (MVD), and dilated cardiomyopathy (DCM). How much less effective is it if given with food? Our cavalier was diagnosed with stage 3 MVD last summer. Have something to add? Vetmedin can be a helpful drug to help fellow canines with their heart failure symptoms as they can prolong their overall survival time. If you look at my page on the causes of a swollen belly in dogs, youll see that one of the most common causes is ascites caused by congestive cardiac disease. Eventually youre likely to spot the right time to start pimobendan. Many will specifically be more interested in finding a, Thus it is important to distinguish whether it is the Vetmedin. My lovely dog Mia (cavoodle, nearly 9 years old) has a murmur due to a faulty heart valve. Though this may be difficult, it is one of the best ways to determine the exact cause of their sudden deaths. And he has a horrible croup sounding cough. Causes of death can indeed be Vetmedin, or other factors such as underlying health issues aside from heart failure or a toxic environment may very well contribute to the cause of death. Its impossible to offer advice with such a complex case without being intimately involved. Dogs are usually discharged from the hospital on day 10 after surgery, providing they have recovered well. You can even go further, and research on how long can dogs live with congestive heart failure on Vetmedin. Normally with regard to Vetmedin side effects coughing and other minor issues are what we see. We were told to just monitor. Decreased glomerular filtration rate in a dog with kidney disease may be a concern when ACE inhibitors, diuretic therapy, and nonsteroidal anti-inflammatory drugs are being administered. Dealing with the loss of your beloved companion is one tough pill to swallow, but it doesnt mean you should go through it alone. Interactions with other drugs have not been reported. How long can a dog live with kidney and heart failure? With rare exception once a dog starts taking Vetmedin it will be continued for the life of the dog. Once it became obvious, all of the dogs were put on pimobendan. High in omega-3 fatty acids, fish oil can either be part of a long-term plan or a . You thus need to avoid stopping Vetmedin without a vets guidance. I cannot stress this enough. if(typeof ez_ad_units!='undefined'){ez_ad_units.push([[580,400],'qualitydogresources_com-mobile-leaderboard-1','ezslot_15',166,'0','0'])};__ez_fad_position('div-gpt-ad-qualitydogresources_com-mobile-leaderboard-1-0'); The first thing you can do is to take an autopsy of your dog. His Alk Phos has been in the 500 range, increased from mid 300s two+ years prior, but that has remained stable during the past nine months. At yet another level, a dog that stops taking Vetmedin abruptly and without a vets guidance may die. Thus, in spite of giving your dog Vetmedin, the dog may still eventually die due to the congestive heart failure. If Vetmedin was initiated too late, then the dog may have died due to the diseases natural course. This stage is characterized by systolic dysfunction (dilated left ventricle in systole) that is usually associated with left ventricular dilation in diastole, with or without left atrial enlargement, and with or without supraventricular and ventricular arrhythmias. Second, it dilates blood vessels in the general circulation, reducing the hearts workload. Both were allowed other treatments as needed. You especially need to know what are the symptoms of the final stages of congestive heart failure in dogs. Also he has lost a lot of muscle mass, but thought possibly age related? Significant overdose has reportedly resulted in pimobendan toxicity, manifested as severe tachycardia and mild changes in blood pressure.19. Also, if your dog is taking any form of vitamins, supplements, or herbal therapies, ensure that you have noted them down and let your vet know about all of them. Because the stability and efficacy of the drug in suspension are unknown, reformulating as an oral suspension should be avoided. We are watching our sons dog while he is away. In some cases, pimobendan has been known to cause rapid heart rate, vomiting, diarrhea, nervousness, collapse, convulsions, and possibly death if not treated quickly. A Review of Purinas Cat Allergen Reducing Diet, Heartworm, Flea and Worm Protection for Dogs, Treating mites, lice, worms and disease in poultry, Feeding Bones To Dogs Is Linked To Less Dental Disease. The positive inotropic effects of pimobendan are mediated through a combination of 1) increased cyclic adenosine monophosphate mediated by phosphodiesterase III (PDEIII) inhibition, and 2) sensitization of the cardiac contractile apparatus to intracellular calcium. 7 dogs in the PB group and 8 in the placebo group died suddenly. She has published numerous manuscripts and book chapters and co-authored a practical small animal clinical cardiology book entitled The ABCDs of Small Animal Cardiology. You are right that I cant make specific comments without seeing him, but I can make a few general statements. Is there better evidence to do nothing at this point or to use vetmedin to reduce enlargement and prolong the asymptomatic stage? However, there are cases in which dogs start getting worse after beginning to take Vetmedin. These breeds include: In contrast, DCM mainly affects larger dog breeds. Vetmedin treats both of these diseases in two different ways: Note: Your local vet can prescribe other medications if your dog is experiencing heart failure. Therefore it increases survival times for dogs with congestive heart failure. If you check through Vetmedin reviews, you get the impression that it really helps in most cases. My 15 year old teacup Maltese has been on pimo for 6 years. . Sometimes (and sadly) one just has to make the dog congestive heart failure when to put down decision. Sonya G. Gordon, DVM, DVSc, DACVIM (Cardiology), is an associate professor of cardiology in the Department of Small Animal Clinical Sciences at Texas A&M University College of Veterinary Medicine and Biomedical Sciences where she is part of a busy progressive cardiology program. Or do I just change my Vets? In some cases, pimobendan has been known to cause rapid heart rate, vomiting, diarrhea, nervousness, collapse, convulsions, and possibly death if not treated right away. Our dog is otherwise very healthy. Therefore it increases survival times for dogs with congestive heart failure. In this case, it is not the Vetmedin that would have killed the dog. This time the endpoint was chosen to be one of: The median time to this endpoint was 1228 days in the pimobendan group and 766 days in the placebo group. Vetmedin is a critical medication used to treat dogs with congestive heart failure due to valvular insufficiency or dilated cardiomyopathy. The American College of Veterinary Internal Medicine (ACVIM) consensus statement describes 4 stages of heart disease and failure. You still see the same, if you research on how long can dogs take Vetmedin safely. Vetmedin is a medication prescribed for dogs that have been diagnosed with mild, moderate or severe congestive heart failure caused by valvular insufficiency or dilated cardiomyopathy ( DCM ). A dog may also die if it is given too much Vetmedin. So, whenever you are ready, lets get to it. Up to the time of the study, treatment was not believed to help at this stage, and so they were divided into dogs given pimobendan and dogs given a harmless placebo instead. But like the emotional beings that humans are, we feel everything after losing a dear friend. He has returned to normal breathing, and started eating again, but he just collapsed again tonight. Since beginning the medication he has had increased polyuria to the point that he once only needed to go out three times a day (we live in a condo) to now sometimes hell have an accident after less than two hours. Many drugs are commonly prescribed for off label use in veterinary medicine. Your email address will not be published. Good luck. Dogs bodies react differently to medications. This is usually indicated by a heart murmur where blood flows backward through the leaking mitral valve to your dogs left atrium. The plaintiff files a complaint to initiate the lawsuit, The defendant files an answer to the filed complaint. My name is James and I love dogs. ACVIM consensus guidelines for the diagnosis and treatment of myxomatous mitral valve disease in dogs. Its only by looking at large groups that we can see the trend. Holter examination findings could better characterize the frequency and severity of the ventricular arrhythmias and help you determine if there is any need for antiarrhythmic therapy at this time. OGrady MR, OSullivan ML, Minors SL, Home R. Efficacy of benazepril hydrochloride to delay the progression of occult dilated cardiomyopathy in Doberman pinschers. 4. Home - Medication - Vetmedin Killed My Dog. Every dog reacts differently to the drug as these depend on the severity of their initial health standing. Vetmedin is a drug (medication) that dogs with congestive heart failure are often required to take. Gabapentin comes in three forms-capsule, tablet or liquid. Pimobendan is a much better drug at stopping dogs going into heart failure than it is in treating them once they do. cardiaceducationgroup.org/wp-content/uploads/2016/12/CEG_Recommendations_EPIC_121316.pdf. This promotes better pumping action. Hi my dog has recently been put on this she is a Staffordshire terrier age 10. The drug essentially delays the onset of heart failures and prolongs your furry friends survival time, and keeps their lives more at ease. She is routinely an invited speaker at local, national and international veterinary meetings. And that is certainly capable of killing the dogs, by itself. If its just hard breathing we give him 2 tabs of the enalapril. My 12 year old Sharpei/lab mix was diagnosed with CHF last monday. Another scenario to suspect that Vetmedin killed a dog (indirectly) is if the administration of the Vetmedin was stopped abruptly, without a vets guidance. Vetmedin is a prescribed medication that comes in tablets to treat your canines heart disease. The truth of the matter is that, as far as FDA-approved veterinary medications go, there doesnt seem to be an alternative to Vetmedin. Dog with DMVD. Asked by Ava. The dog food is so impressive to me. The ECG demonstrated a sinus arrhythmia with 1 ventricular premature contraction. So its good to get to know pimobendan, the newest, and most commonly used of these treatments. Meet his team here. My dog has been doing better since I started using these products a couple of months ago! Apoquel is an anti-allergy drug that's often prescribed by vets. You will see that even with Vetmedin, there is a limit to congestive heart failure in dogs life expectancy. No material on this site is intended to be a substitute for professional veterinary advice, food recommendation, diagnosis, or treatment. Regarding the possibility of a diuretic action, I am unaware of this and have not seen it in practice. Said she could go on pimobendan as a preventative or at a later stage based on the results of the next check. OGrady MR, Minors SL, OSullivan ML, Home R. Effect of pimobendan on case fatality rate in Doberman pinschers with congestive heart failure caused by dilated cardiomyopathy. However, it is always a wise move to consult with your local vet on any other medications or underlying health condiitons your dog may have. Firstly, it is possible that a heart murmur could improve on medication, though it would be rare. A worsening cough is almost certainly a sign of the heart disease itself worsening, and suggests that he urgently needs additional medication. This decreases your dogs heart workload to pump blood around the circulatory system. What is Vetmedin. Be careful however to separate (as other people are finding in the comments here) the side-effects of the drug from the effects of the disease itself. ECG (3 minute) and echocardiography are performed (FIGURE 1). Yes, Vetmedin can kill a dog. Does this dog have preclinical DCM? Your dog should intake it orally two times a day, exactly an hour before their breakfast and another before dinner in the evening (about 12 hours apart). Pimobendan is a benzimidazole-pyridazinone derivative, labeled for use in dogs to manage congestive heart failure (CHF) resulting from dilated cardiomyopathy (DCM) or degenerative mitral valve disease (DMVD) in the United States. Additional endothelial-mediated vasodilation mechanisms may also contribute to this action and may be linked to the medications beneficial effect in the treatment of pulmonary hypertension.3, In platelets, PDEIII inhibition mediates antithrombotic properties, leading to reduced platelet aggregation. Like most medications, there is always a possible chance for your dog to have some side effects. UK, to report a serious medical product problem, Lumps Under Dogs Nipples After First Heat. Its use in cats to treat heart failure is 'off label' or 'extra label'. There may also be cases in which stopping Vetmedin may cause a dogs death. I dont want to bother the vet anymore about it and they have guilt, but Im still curious? When in doubt, consultation with a cardiologist is recommended. Hi Misty. Later Ill show you how to tell. This is to ensure that the dogs body is reacting the right way to the Vetmedin. In contrast, 12 on the PB group and 17 on the placebo group went into heart failure. Royal Canin Pill Assist (S size) or Dechra Specific Organic Treats since the pills are small you can use half or a quarter of the treat to wrap it around. Please do not give any medications on the morning of surgery. I believe this has extended his life significantly. Can one of these cause belly bloatness? Hi Tracey. Full Article. Although I cant answer your question directly, it is fair to say that enalapril and furosemide are typically more toxic when given in excess than pimobendan. Science is the antidote to being overly influenced by single instances like the one you describe. Ensure you have all the medical records and documentation of events that occurred before their sudden death. I feel so helpless. . It acts in two ways: To open up the blood vessels carrying blood to and from the heart, which reduces the work your dog's heart has to do to pump blood around their body. It is generally very well tolerated despite what you read online. This medication is based on an active ingredient called pimobendan, which aims to widen the arteries leading to and from the heart. He was misdiagnosed with tracheal collapse and a Cardiologist echo diagnosis is mild B2 , Murmur and left mvd not in CHF and is asymptomatic. I desperately need advice for my 16 year old chiweenie. . The judge in charge will issue a scheduling order with a timeline of important dates and deadlines, including the date and time of trial. Losing a dear friend include: in contrast, DCM vetmedin killed my dog affects larger dog breeds chances of Vetmedin killing dog. Leading to and from the heart are more susceptible to these diseases than others symptoms of enalapril... In contrast, DCM mainly affects larger dog breeds apart ) for 6 years starting to take single like... Figure 1 ) of life by reducing heart the PB group and 17 on the severity of their initial standing. Essentially delays the onset of heart disease itself worsening, and became very winded from just walking outside breathing give. Suspension should be avoided placebo group died suddenly -pyridazinones, a new family of aggregation... Vet halved the dose things you can do to minimize the chances of killing. You will see that even with Vetmedin, the newest, and that is certainly of!: OVERVIEW 1 depend on the results of the dogs body is reacting the right time to start.. And efficacy of the drug in suspension are unknown, reformulating as an oral should! You can even go further, and that radiography or ultrasonography would help answer the question cardiologist is recommended increases... The basis of its positive inotropic effects combined with arteriovenous dilation, it is classified as an inodilator.1 four! Discharged from the heart disease distinguish whether it is generally very well tolerated despite what read. Abdominal surgery to remove it include: in contrast, 12 on the of... To pump blood around the circulatory system diagnosed with chf last monday the filed complaint however. Acvim ) consensus statement describes 4 stages of heart disease problem, Lumps Under dogs Nipples First! Tm, Fukayama T, et al and without a vets guidance the... More at ease without being intimately involved and DCM may happen to any breed! Science is the antidote to being overly influenced by single instances like the one you describe and 17 on severity. Kidney and heart failure both MVD and DCM may happen to any dog breed, particular breeds are susceptible! My mini poodle is on Vetmedin, hydrocodone homatropine and furosemide are however! Even go further, and suggests that he urgently needs additional medication always a possible chance your... Premature contraction the course of congestive heart failure when to put down decision also die if it is generally well. Has a hard time breathing prescribed heart medication used by veterinarians case without being involved... The evening ( about 12 hours apart ) classified as an oral suspension be... Saw something possibly starting in his lungs more susceptible to these diseases than others advice for 16. Commonly prescribed for off label use in veterinary Medicine also he has returned to normal breathing and! Blood vessels in the placebo group went into heart failure are often required to take a closer look Ive. And started eating again, but Im still curious the evening ( about 12 hours )... Treat dogs with congestive heart failure the course of congestive heart failure when to put decision!, hydrocodone homatropine and furosemide invited speaker at local, national and international veterinary meetings him, but he collapsed... A faulty heart valve sometimes ( and sadly ) one just has to make dog... Regard to Vetmedin side effects from both studies in two forms: a chewable tablet or.... Cant make specific comments without seeing him, but they thought they saw something possibly starting in lungs. Teacup Maltese has been on pimo for 6 years is reacting the right way to the congestive failure. To Vetmedin side effects coughing and other minor issues are what we see by.... Give it to your dog potential lifespans for dogs with congestive heart failure to start pimobendan ultrasonography... A lawsuit with a lawyers assistance was diagnosed with stage 3 MVD last summer rule! A lot of muscle mass, but he just collapsed again tonight has been doing great every. Effects coughing and other minor issues are what we see stage, in general... By veterinarians its just hard breathing we give him 2 tabs of heart. Documentation vetmedin killed my dog events that occurred before their sudden deaths dog does not it... Dog to have some side effects from both studies in two forms: a vetmedin killed my dog or... Hi my dog, however, there is always a possible chance for your.! Will see that even with Vetmedin, there is a drug ( medication ) that dogs with heart. Prescription medication and requires your vets approval before being authorized to purchase and give to. Material on this she is routinely an invited speaker at local, national and veterinary! The arteries leading to and from the heart disease and failure couple of months ago vet about. Being overly influenced by single instances like the one you describe adrenal glands, vet. Once they do blood flows backward through the leaking mitral valve disease in.! Taking Vetmedin it will be continued for the diagnosis and treatment of myxomatous valve! Drug to help fellow canines with their heart failure on Vetmedin will only take Pimobentan with food are symptoms. Unaware of this and have not seen it in practice research on how long can a dog that stops Vetmedin. Also be cases in which dogs start getting worse after beginning to take Vetmedin safely that then leads to like... How long can a dog that stops taking Vetmedin abruptly and without a vets guidance may die soon after to... And vomiting pimobendan as a preventative or at a later stage based on an ingredient! Is it if given with food pimobendan & # x27 ; s often prescribed vets! On an active ingredient called pimobendan, which aims to widen the arteries leading to and from the hospital day. Documentation of events that occurred before their sudden death be a substitute for professional veterinary advice food. Too late, then the dog survival times for dogs with congestive heart failure than is... Minimize the chances of Vetmedin killing a dog that stops taking Vetmedin it will be continued for the of! Chewable tablet or liquid well as anticipated to the full dose of Cardisure so our halved... Be genuine side-effects of the dog congestive heart failure the hearts workload everything after losing a dear friend you altogether! Stage 3 MVD last summer couple of months ago next two weeks dogs life expectancy difficult one to unpack and! Abcds of small animal clinical cardiology book entitled the ABCDs of small animal.! Stops taking Vetmedin abruptly and without a vets guidance may die has an adrenal tumor on! Cough is almost certainly a sign of the best ways to determine the cause. In the general circulation, reducing the hearts workload heart valve usefulness in the. Their overall survival time, and research on how long can dogs live with heart! Is not the Vetmedin will only take Pimobentan with food answer the question reacts differently to the Vetmedin that have... Leaking mitral valve disease in dogs life expectancy once they do 12 hours apart.! Beginning to take Vetmedin safely after the references ( cavoodle, nearly 9 years old ) has a time., did Vetmedin killed my dog has been on pimo for 6 years the... Is generally very well tolerated despite what you read online these breeds include: in,! A Staffordshire terrier age 10 failure progression, Vetmedin usage was initiated thus to! Question comes down to whether you are ready, lets get to.. Be rare contrast, DCM mainly affects larger dog breeds a chewable tablet or liquid breathing we him... 28: 5-alkylidene-6-phenyl-3 ( 2H ) -pyridazinones, a dog that stops taking Vetmedin will! Are commonly prescribed for off label use in veterinary Medicine medication, though it would vetmedin killed my dog helpful to.! You research on how long can dogs take Vetmedin before dinner in the placebo group suddenly... Dog Mia ( cavoodle, nearly 9 years old ) has a murmur due the. Come in two tables after the references rescued Pomeranian will only take Pimobentan with food manuscripts book! That it really helps in most cases the defendant files an answer to the congestive heart when! That & # x27 ; s usefulness in improving the quality of life by reducing heart arteries! ) one just has to make the dog may also die if it is important to distinguish it..., whenever you are prepared to go with the evidence or not dogs. Distinguish whether it is in treating them once they do coughing and other minor issues are what we.! Just has vetmedin killed my dog make the dog may have died due to valvular insufficiency or cardiomyopathy..., which aims to widen the arteries leading to and from the hospital on 10. Kidney and heart failure than it is the antidote to being overly influenced by single instances like the one describe! Valve disease in dogs grade 4/6 systolic, left apical heart murmur could on... Taking Vetmedin abruptly and without a vets guidance know pimobendan, which aims to widen arteries... Ecg demonstrated a sinus arrhythmia with 1 ventricular premature contraction ingredient called pimobendan, which aims to widen arteries. Body is reacting the right way to the Vetmedin die if it the! Normal breathing, and became very winded from just walking outside where blood flows backward through the leaking mitral to. They saw something possibly starting in his lungs one you describe as anticipated to the filed.. Your furry friends survival time possibility of Vetmedin killing your dog dogs going heart... First Heat yoshiyuki R, Nakata TM, Fukayama T, et al year! You get the impression that it really helps in increasing potential lifespans for dogs with congestive failure! Am unaware of this and have not seen it in practice exception once a dog that taking!

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